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Espread ownership of mobile phones has been made possible by an enabling environment in Kenya where the last few years have seen an increase in availability of a range of mobile phones (both low cost and high end) but it is noteworthy that none of the hospitals studied provide free Internet access for frontline health workers. Internet costs have dropped due tocompetition among service providers;
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Greetings everyone. What a week we had! Hurricane Irma really packed a punch, many of us are still without electricity or water. Despite the stress we are already experiencing we have to bring your attention to the threat Leptospirosis, Lepto for short, is to your pets. Lepto is considered an Emerging Bacterial Disease by the CDC and can affect humans as well (that means you)! Lepto is usually ass
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E audio-recorded and transcribed verbatim into Microsoft Word files by an independent transcriber. Interviews continued until saturation of themes had been achieved. This was determined when no new themes were arising across the interviews. This process resulted in a total of N = 20 participants (n = 13 symptomatic, n = 7 improved).AnalysisHeight and weight data were used to calculate body mass in
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For two novel experiments and three norming tasks, which are alsoFor two novel experiments and three norming tasks, which are also available at https://osf.io/r8mac/, along with analysis files. The samples and methods for the novel studies are described in this section.PLOS ONE | DOI:10.1371/journal.pone.0133939 July 28,2 /Metaphorical ReasoningEthics StatementThe experiments reported here w
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Sion and Negative groups (p < 0.05, Kaplan-Meier). b High expression level of ALDH1 in tumor cells in ovarian carcinomas was significantly associated with high PFS probabilities (p < 0.05, Kaplan-Meier). c The expression level of ALDH1 in the stromal cells in ovarian carcinoma had no significant association with OS probabilities (p > 0.05, Kaplan-Meier). d No statistical association was found betw
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Owever, there were other studies indicating a better clinical outcome in ALDH1(+) cancer patients, using different antibodies. Our previous study, using rabbit polyclonal antibody against human ALDH1A1 (ab63026, Abcam, Cambridge, UK) has proved that ALDH1 expression in vulvar squamous cell carcinomas predicted a significantly better survival than the ALDH1 negative cases [28]. Similarly, Hessman a
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Nt years [32]. In their study, dual positive cells of ALDH1 and another traditional ovarian CSC marker CD133 were isolated directly from human tumor to initiate tumor in mice, and these cells displayed enhanced angiogenesis and tumorigenicity like other CSCs [32]. Moreover, the patients with CD133(+)/ALDH1(+) tumor cells displayed reduced PFS and OS [32]. Distinct expression levels and patterns of
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Expression in the tumor microenvironment is rather different in the above findings. Resetkova et al. hold the opinion that high expression of ALDH1 in breast cancer stromal cells had a best disease free survival and a trend of better overall survival [42], De Brot et al. confirmed that ALDH1 frequent expression in tumor-associated stromal cells of triple negative breast cancer predicted a better o